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Board-certified orthodontic practice in Pennington, NJ offering braces, Invisalign, and comprehensive orthodontic treatment for children, teens, and adults.

About DeSimone Orthodontics
Board-certified orthodontic practice in Pennington, NJ offering braces, Invisalign, and comprehensive orthodontic treatment for children, teens, and adults.
Known for state-of-the-art technology including digital scanning, virtual smile design, and reduced radiation exposure.
Treatments offered
Who They Treat
DeSimone Orthodontics provides orthodontic treatment for the following age groups:
Technology & Equipment
DeSimone Orthodontics uses modern orthodontic technology to deliver precise, comfortable treatment.
Orthodontists at this office
Dr. Karen E. DeSimone, DDS
NPI verified · no bio or photo on file
Dr. Nick Kelley, DMD, MSD
NPI verified · no bio or photo on file
Insurance accepted
Patient reviews
Sourced from Google
I’ve been going to Dr. DeSimone and DeSimone Orthodontics for almost a decade, and I truly can’t say enough good things about my experience. I had a very difficult case, and throughout the entire process, Dr. DeSimone was incredibly thoughtful and skilled in finding the best approach for me. I was able to use Invisalign for several years with expertly placed attachments that helped me avoid having to wear more cumbersome gear or traditional braces, which I really appreciated. Even years later, the level of care has remained just as great. I recently came back because I needed to have a retainer remade, and they were able to take my impressions and have a new retainer ready for me that same day. Both of my siblings have also been patients of Dr. DeSimone and have had similarly great experiences, so our family has been coming here for years. Dr. DeSimone and the entire staff have always been incredibly friendly, accommodating, and genuinely great to work with. I would absolutely recommend DeSimone Orthodontics to anyone looking for an orthodontist they can trust.
I have been going to Dr.DeSimone since I was 15 years old. She did a wonderful job with my invisalign journey when I was a teenager, and absolutely did not disappoint as an adult when I returned for additional treatment. They are a kind and welcoming staff who truly wants the best for their clients. If you live in the Pennington area, I 10/10 recommend Dr.DeSimone and Kelly orthodontics!
Both of my sons had braces with Dr. DeSimone and had two fantastic experiences! I’m a stickler for customer service and the entire staff is incredible - consistently friendly, knowledgeable and professional. They’ve created a warm environment for patients and their families - something that was very important for me when looking for an orthodontist in addition to a high standard of treatment. Can’t recommend them more highly.
Dr. Desimone is the best! The epitome of strong expertise and strong customer service for patients of every background. Sharp and kind, everyone in the facility are folks that are going to accommodate and support you to the best of their ability.
I noticed my teeth had shifted in adulthood and had been thinking about Invisalign, and I’m so glad I scheduled a consultation with Dr. DeSimone. From day one, the treatment plan was clear, thoughtful, and easy to understand, and the timeline stayed perfectly on track. Check-in appointments were always quick and seamless. Dr. DeSimone is an absolute perfectionist—in the best way—paying incredible attention to detail and finding creative solutions every step of the way. The entire staff is genuinely warm, welcoming, and always happy to answer questions, which made the whole experience feel comfortable and stress-free. I truly couldn’t be happier with my experience!
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